Planned Coincidence

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This concept is now being applied more broadly to the search for novel types of chemical reactions, particularly in the search for new, easier, faster, or more elegant synthetic pathways for natural products, specialty chemicals, and drugs. Reactants A and B are added to the wells of a microtiter plate. In some wells, various transition metals are added as possible reaction promotors. Reactant A carries a marker that is recognized and bound by antibody AK1; reactant B carries a marker for antibody AK2. If a coupling occurs, the product has both markers.

After the reaction, the solutions are transferred to new plates that are coated with AK1. After a washing step, only molecules with a binding site for AK1 remain on the plate. A solution of AK2 is next applied, followed by another washing step. Successful reactions are made visible by an enzyme that is bound to AK2 and causes the color to change to yellow.

I have a friend who is far more powerful than I am. When he tells his children to go upstairs, they immediately scamper up like rabbits.

Power is a relationship between people in which a dominating will is imposed upon a subordinate will. It is measured, therefore, as a ratio. The dominant will is powerful only to the extent that the subservient will is subservient. None can gain power except by gaining power over someone.

The test of power is none other than that which the centurion explained to Jesus: "When I say to a man go he goeth and when I say to a man come he cometh". To say that a king "Had power" is meaningless; one must say that the king had power over the nobles, over parliament, over the army. And even that statement is meaningless unless it is understood that the words nobles, parliament, or army were not mere abstract nouns, but simple collective terms which refer to a certain number of actual human beings.

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When the children were quarrelling the other day I literally pulled them apart; I was using force, not power. Force is a relationship between bodies, not between wills. It is not the same as power, though it may contribute to the establishment of a power relation. When an executioner springs the trap, or a company of soldiers makes an attack, [p.

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Force is seen in the relation of the executioner to the condemned man, or of the soldiers to the enemy. There is property in my family. I have my pipe, the children have their toys. Such things are called "inalienable". In the extensiveness of the group itself, in the specific internal relations of power within the group, in the practices followed in the use of force and in the system of property no two families are exactly alike. Any two families differ as Cleveland differs from Manchester, as France differs from Spain. The internal order of each family arises out of the balance of personalities and the course of events, and is constantly changing.

The subtleties of internal custom, the intricacies of causes of conflict, the variety of procedures used in their adjustment are such that no externally compounded rules can be a substitute for the internal forces of family life, and no general description of type exactly fits any specific case. Power is always a relationship of wills, force is always a relationship of bodies, and property is always that from which other people may be excluded. Within any group it is impossible that one person should have absolute and unlimited power, and another person enjoy an absolute and unlimited right of property.

If the parent can confiscate the child's toy, or compel the child against his desire to share its use, then the child's property in the toy is not absolute and unlimited. If the parent cannot confiscate the child's toy, nor compel the child against his desire to share its use, then the power of the parent is not absolute and unlimited. The exercise of power is intrusive, the enjoyment of property exclusive. Neither can [p. This principle, exemplified in family life, is found equally in the relations of rulers of states to the people in them.

The name which is used to designate state-power is "sovereignty". Many thinkers regard sovereignty as unlimited and absolute power within the state group.

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The "sovereign will", they say, is that to which all wills must yield in all things. If this is indeed the nature of sovereignty to be absolute and unlimited, then it is only by self-restraint, and not otherwise, that a sovereign will refrains from overriding the desires of those persons within the state who claim the exclusiveness of property rights. If on the other hand the property rights of the people within the state are indefeasible, then the sovereignty of the state is not absolute and unlimited.

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Between these two inconsistent extremes every state, like every family, makes a compromise. The terms of this compromise are the law. The law defines the circumstances under which a person may exclude others from the enjoyment of things and services without having his wishes overridden by the sovereign will.

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Thus a man may eject a trespasser from the city lot which is his property but may not build a glue factory upon it. When I reflect upon the regularities and routines of my family I recognize that there is law in its life, just as there is power , force and property. And this law seems to me to be of three kinds. One kind of law determines who is to be obeyed by whom under what circumstances.

It is law in relation to power. It is simply the stabilization of our power relations. As such it is always the product of time and habit, and for that reason it changes with time, an the children grow older, and as new situations arise. Another kind is the law we make when we say "hereafter we will do thus and so". We make this law by agreement, bargain or contract, by mutually conceding some exclusive liberties. It is the kind of law that is most nearly related to the property principle of individual exclusiveness, just as the habit-of-obedience kind of law is most nearly related to the power principle of subordination.

We do not always adhere to the law of our family. There are doubtful types of halfway per- [p. In some cases some of us acknowledge or declare that our family law is not all that it should be. The first kind of law is mostly defined by what we have done, the second by what we say we will do, the third by what we think we ought to do.

These three kinds of law, I believe, are found not only in my family, but throughout organized mankind. The first is the legal aspect of power, the second the legal aspect of contract or exchange, the third the legal aspect of opinion. The expression "might makes right" refers to the first kind of law, for a power relation may be established by using bodily force and in the passage of time this will become a species of law. The expression "government by consent of the governed" refers to the second kind of law, for rules of conduct may indeed be agreed upon by those to whom they apply.

The phrase "moral law" refers to the third kind of law, for moral law is found and stated in the ethical judgments that people make about conduct, either their own conduct, or the conduct of others. In different families, even within the same city, power relations may vary from dictatorships that are unattainable in any state to democracies that would be unworkable at any higher level of human organization.

Property tenures vary from extremes of communism to applications of the principle of indefeasible ownership that would wreck any larger society if indiscriminately applied. Duties, responsibilities, privileges, privacies, establish themselves by usage, undergo modification in practice and though never formulated in a code constitute always a standard of behavior, always applied according to circumstances, never wholly rigid, never wholly capricious.

The child's tenure of his bed, and of his place at the table, the father's right to the first reading of the newspaper, modified perhaps by a child's right to the comic strip, the claims upon services in kitchen or garden, the restraints upon the use of toys in noisy or boisterous play, are all elements of a property system.

Rights of transaction by gift or exchange, use-rights and prescriptive rights of all kinds are established in a complexity that makes corporation finance look comparatively simple. At this point the author must appeal to the reader to share his work. A blank page must stand here which you must fill out for yourself.

First, who are the members of your family group, who are nearest, and who are more distant? This is the definition of a group. It is better than any definition in any book. Third, what is property in your family? To answer this question begin with an analysis of the terms and conditions governing the use of the family car. Fourth, what law is found in your family? When you have filled out this page put your name with mine on the title page of this book. You have become co-author with me, though to answer these questions in full you might have to write another book as big as this one.

Despite the range of individual variation between specific families, it is possible to set up the notion of a typical family of a given time and region, and to contrast typical families of one period with typical families of another. Such contrasts show changes which have occurred through the ages in the typical families of Europe. An account of these changes is not the history of any family, such as Wedgwood, Jukes or Coburg, but of "the family", the institution, the abstraction.

The extensiveness of the typical family group has narrowed through the past three ages. In the Barbarian Age families were more like clans. The great-grandchildren of some one man, together with slaves and dependants, would be found sticking together as a household, usually choosing some elder member as a head. This patriarchal type of family was still widespread in Europe in the [p. In the Balkans it can still be found. But in general the "small family" type became standard in the modern age, and is so today.

In the small family the parents and children are the household, and at the same time the nucleus or center of a larger kinship group which includes more or less distant relatives of both husband and wife. The territory of a family is its home. The physical frontier is the frontier of its living space, the door of its apartment, the threshold of its house.

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